产品英文名称 | Galectin-3 Monoclonal Antibody |
免疫原 | 蛋白 |
宿主 | 小鼠 |
反应性 | 人, 大鼠, 小鼠 |
应用 | ELISA, IHC-P, WB |
实验建议 | 最佳的工作稀释比例需要客户摸索优化。建议的起始尝试的稀释比为:WB:1:2000-1:5000,IHC-P:1:100-1:200。 |
克隆性 | 单克隆 |
纯化工艺 | 使用表位特异性的免疫原,通过亲和层析,从小鼠腹水中亲和纯化抗体。 |
产品形式 | 液体溶液 |
浓度 | 1 mg/ml |
储存缓冲液 | 含有50%甘油,0.5%BSA和0.02%叠氮化钠的PBS缓冲液。 |
保存建议 | 自发货之日起,-20°C可稳定保存1年。为最大限度的避免损失,请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。 |
运输条件 | 蓝冰运输 |
警告 | 本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。 |
背景 | LGALS3 (galectin 3) encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants. |
基因ID | 3958 |
别名 | LGALS3; MAC2; Galectin-3; Gal-3; 35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; IgE-binding protein; L-31; Laminin-binding protein; Lectin L-29; Mac-2 antigen |
其它 | 该抗体可检测内源蛋白 |
蛋白质ID | P17931 |
Fig.1. Western blot analysis of 1) MCF7, 2) 3T3 with Galectin-3 Mouse mAb diluted at 1:2000.
Fig.2. Immunohistochemical analysis of paraffin-embedded human-colon using antibody diluted at 1:50.
Fig.3. Immunohistochemical analysis of paraffin-embedded human-colon2 using antibody diluted at 1:50.
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