ABCG2多克隆抗体

ABCG2 Polyclonal Antibody

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商品信息

产品英文名称	ABCG2 Polyclonal Antibody
免疫原	合成多肽：人源蛋白的中央区域， ABCG2
宿主	兔
反应性	人
应用	ELISA, IF, IHC-P, WB
实验建议	最佳的工作稀释比例需要客户摸索优化。建议的起始尝试的稀释比为：WB：1:500-1:2000，IF：1:50-1:200，IHC-P：1:100-1:300，ELISA：1:10000。
克隆性	多克隆
纯化工艺	使用表位特异性的免疫原，通过亲和层析，从兔抗血清中亲和纯化抗体。

商品属性

产品形式	液体溶液
浓度	1 mg/ml
分子量	75 KD
储存缓冲液	PBS缓冲液（pH 7.4），含有0.5%BSA（稳定剂），0.02％叠氮化钠（防腐剂）和50％甘油。
保存建议	自发货之日起，-20°C可稳定保存1年。为最大限度的避免损失，请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。
运输条件	蓝冰运输
警告	本文列出的产品仅供研究使用，不适用于人类或临床诊断。我们产品所推荐应用，不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为，我们不承担任何责任。

附加信息

背景	ATP binding cassette subfamily G member 2 (Junior blood group) encoded by ABCG2 is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.
基因ID	9429
别名	ABCG2; ABCP; BCRP; BCRP1; MXR; ATP-binding cassette sub-family G member 2; Breast cancer resistance protein; CDw338; Mitoxantrone resistance-associated protein; Placenta-specific ATP-binding cassette transporter; CD338
其它	该抗体可检测内源蛋白
蛋白质ID	Q9UNQ0

图片及说明

Fig.1. Western Blot analysis of 3T3 (1， 293 (2， diluted at 1:500.

Fig.2. Immunofluorescence analysis of human breast cancer tissue. 1, ABCG2 多克隆 Antibody (red) was diluted at 1:200 (4°C, overnight). 2, Cy3 Labeled secondary antibody was diluted at 1:300 (room temperature, 50min). 3, Picture B: DAPI (blue) 10min. Picture A: Target. Picture B: DAPI. Picture C: merge of A+B.