| 产品英文名称 | ERα (phospho Ser118) Polyclonal Antibody |
| 免疫原 | 合成多肽：人源蛋白ERα，磷酸化多肽，中心氨基酸为S118. |
| 宿主 | 兔 |
| 反应性 | 人, 小鼠 |
| 应用 | ELISA, IHC-P, WB |
| 实验建议 | 最佳的工作稀释比例需要客户摸索优化。建议的起始尝试的稀释比为：WB：1:500-1:2000，IHC-p：1:100-1:300，ELISA：1:20000。 尚未在其他应用中测试。 |
| 克隆性 | 多克隆 |
| 纯化工艺 | 使用表位特异性的免疫原，通过亲和层析，从兔抗血清中亲和纯化抗体。 |
| 产品形式 | 液体溶液 |
| 浓度 | 1 mg/ml |
| 储存缓冲液 | 含有50％甘油，0.5％BSA和0.02％叠氮化钠的PBS缓冲液。 |
| 保存建议 | 自发货之日起，-20°C可稳定保存1年。为最大限度的避免损失，请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。 |
| 运输条件 | 蓝冰运输 |
| 警告 | 本文列出的产品仅供研究使用，不适用于人类或临床诊断。我们产品所推荐应用，不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为，我们不承担任何责任。 |
| 背景 | ESR1 encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein (estrogen receptor 1) localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. |
| 基因ID | 2099 |
| 别名 | ESR1; ESR; NR3A1; Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1 |
| 其它 | 该抗体可检测内源蛋白 |
| 蛋白质ID | P03372 |
Fig.1. Western Blot analysis of various cells using Phospho-ERα (S118) Polyclonal Antibody diluted at 1:2000.
Fig.2. Western Blot analysis of 293 cells using Phospho-ERα (S118) Polyclonal Antibody diluted at 1:2000.
微信公众号
评价
目前还没有评论