产品英文名称 | Claudin-3 Polyclonal Antibody |
免疫原 | 合成多肽:来源于C端的人源蛋白Claudin-3. 氨基酸序列为: 140-220 |
宿主 | 兔 |
反应性 | 人, 大鼠, 小鼠 |
应用 | ELISA, IF, IHC-P, WB |
实验建议 | 最佳的工作稀释比例需要客户摸索优化。建议的起始尝试的稀释比为:WB:1:500-1:2000,IHC-p:1:100-1:300,IF:1:200-1:1000,ELISA:1:40000。 尚未在其他应用中测试。 |
克隆性 | 多克隆 |
纯化工艺 | 使用表位特异性的免疫原,通过亲和层析,从兔抗血清中亲和纯化抗体。 |
产品形式 | 液体溶液 |
浓度 | 1 mg/ml |
储存缓冲液 | 含有50%甘油,0.5%BSA和0.02%叠氮化钠的PBS缓冲液。 |
保存建议 | 自发货之日起,-20°C可稳定保存1年。为最大限度的避免损失,请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。 |
运输条件 | 蓝冰运输 |
警告 | 本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。 |
背景 | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by CLDN3, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. |
基因ID | 1365 |
别名 | CLDN3; C7orf1; CPETR2; Claudin-3; Clostridium perfringens enterotoxin receptor 2; CPE-R 2; CPE-receptor 2; Rat ventral prostate.1 protein homolog; hRVP1 |
其它 | 该抗体可检测内源蛋白 |
蛋白质ID | O15551 |
Fig. Western Blot analysis of various cells using Claudin-3 Polyclonal Antibody diluted at 1:2000.
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