产品英文名称 | VE-Cadherin Mouse Monoclonal Antibody (3G8) |
免疫原 | 合成多肽: VE-Cadherin |
宿主 | 小鼠 |
反应性 | 人, 大鼠, 小鼠 |
应用 | IHC-P |
实验建议 | 最佳的工作稀释比例需要客户摸索优化。建议的起始尝试的稀释比为:IHC-p:1:50-200。 |
克隆性 | 单克隆 |
纯化工艺 | 使用表位特异性的免疫原,通过亲和层析,从小鼠腹水中亲和纯化抗体。 |
产品形式 | 液体溶液 |
浓度 | 1 mg/ml |
储存缓冲液 | PBS缓冲液(pH 7.4),含有0.02%叠氮化钠(防腐剂)和50%甘油。 |
保存建议 | 自发货之日起,-20°C可稳定保存1年。为最大限度的避免损失,请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。 |
运输条件 | 蓝冰运输 |
警告 | 本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。 |
背景 | CDH5 (cadherin 5) encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. CDH5 is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. |
基因ID | 1003 |
别名 | Cadherin-5; 7B4 antigen; Vascular endothelial cadherin; VE-cadherin; CD antigen CD144 |
其它 | 该抗体可检测内源蛋白 |
蛋白质ID | P33151 |
目标条带分子量(KD) | 80-115 |
Fig.1. Immunohistochemical analysis of paraffin-embedded Rat Heart Tissue using VE-Cadherin Mouse mAb diluted at 1:200.
Fig.2. Immunohistochemical analysis of paraffin-embedded Human Heart Tissue using VE-Cadherin Mouse mAb diluted at 1:200.
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