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激活转录因子2 (phospho Ser112)多克隆抗体

ATF-2 (phospho Ser112) Polyclonal Antibody

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商品信息

产品英文名称 ATF-2 (phospho Ser112) Polyclonal Antibody
免疫原 合成多肽:人源蛋白ATF-2,磷酸化多肽,中心氨基酸为S112.
宿主
反应性 人, 大鼠, 小鼠
应用 ELISA, IHC-P, IP, WB
实验建议 最佳的工作稀释比例需要客户摸索优化。建议的起始尝试的稀释比为:WB:1:500-1:2000,IHC-p:1:100-1:300。 IP:2-5 ug/mg lysate。 ELISA:1:20000。 尚未在其他应用中测试。
克隆性 多克隆
纯化工艺 使用表位特异性的免疫原,通过亲和层析,从兔抗血清中亲和纯化抗体。

商品属性

产品形式 液体溶液
浓度 1 mg/ml
储存缓冲液 含有50%甘油,0.5%BSA和0.02%叠氮化钠的PBS缓冲液。
保存建议 自发货之日起,-20°C可稳定保存1年。为最大限度的避免损失,请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。
运输条件 蓝冰运输
警告 本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。

附加信息

背景 ATF2 encodes a transcription factor (activating transcription factor 2) that is a member of the leucine zipper family of DNA binding proteins. Activating transcription factor 2 has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Activating transcription factor 2 binds to the cAMP-responsive element (CRE, an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Activating transcription factor 2 may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this ATF2.
基因ID 1386
别名 ATF2; CREB2; CREBP1; Cyclic AMP-dependent transcription factor ATF-2; cAMP-dependent transcription factor ATF-2; Activating transcription factor 2; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding pro
其它 该抗体可检测内源蛋白
蛋白质ID P15336

图片及说明

Fig.1. Western Blot analysis of various cells using Phospho-ATF-2 (S112) Polyclonal Antibody diluted at 1:500.

Fig.1. Western Blot analysis of various cells using Phospho-ATF-2 (S112) Polyclonal Antibody diluted at 1:500.

Fig.2. Western Blot analysis of A549 cells using Phospho-ATF-2 (S112) Polyclonal Antibody diluted at 1:500.

Fig.2. Western Blot analysis of A549 cells using Phospho-ATF-2 (S112) Polyclonal Antibody diluted at 1:500.

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