| 产品英文名称 | ABCG2 Polyclonal Antibody |
| 免疫原 | 合成多肽：来源于中间区域的人源蛋白ABCG2. |
| 宿主 | 兔 |
| 反应性 | 人 |
| 应用 | ELISA, IHC-P, WB |
| 实验建议 | 最佳的工作稀释比例需要客户摸索优化。建议的起始尝试的稀释比为：WB：1:500-1:2000，IHC-p：1:100-1:300，ELISA：1:10000。 尚未在其他应用中测试。 |
| 克隆性 | 多克隆 |
| 纯化工艺 | 使用表位特异性的免疫原，通过亲和层析，从兔抗血清中亲和纯化抗体。 |
| 产品形式 | 液体溶液 |
| 浓度 | 1 mg/ml |
| 储存缓冲液 | 含有50％甘油，0.5％BSA和0.02％叠氮化钠的PBS缓冲液。 |
| 保存建议 | 自发货之日起，-20°C可稳定保存1年。为最大限度的避免损失，请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。 |
| 运输条件 | 蓝冰运输 |
| 警告 | 本文列出的产品仅供研究使用，不适用于人类或临床诊断。我们产品所推荐应用，不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为，我们不承担任何责任。 |
| 背景 | The membrane-associated protein (ATP binding cassette subfamily G member 2 (Junior blood group)) encoded by ABCG2 is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for ABCG2. |
| 基因ID | 9429 |
| 别名 | ABCG2; ABCP; BCRP; BCRP1; MXR; ATP-binding cassette sub-family G member 2; Breast cancer resistance protein; CDw338; Mitoxantrone resistance-associated protein; Placenta-specific ATP-binding cassette transporter; CD antigen CD338 |
| 其它 | 该抗体可检测内源蛋白 |
| 蛋白质ID | Q9UNQ0 |
Fig.1. Western Blot analysis of various cells using ABCG2 Polyclonal Antibody.
Fig.2. Western Blot analysis of HT29 cells using ABCG2 Polyclonal Antibody.
作者：Li M , Yin D , Li J , et al. 杂志名称：Pharmazie IF：1.266
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