||SLC43A1 belongs to the system L family of plasma membrane carrier proteins that transports large neutral amino acids (Babu et al. 2003 [PubMed 12930836]). supplied by OMIM, Mar 2008]SLC43A1 (Solute Carrier Family 43 Member 1) is a Protein Coding gene. Diseases associated with SLC43A1 include prostate cancer. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. Gene Ontology (GO) annotations related to this gene include neutral amino acid transmembrane transporter activity and L-amino acid transmembrane transporter activity. An important paralog of this gene is ENSG00000254979. Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.