||MAGEA2 (MAGE Family Member A2) is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of MAGEA2 family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. MAGEA2 has two identical copies at different loci. Alternatively spliced transcript variants encoding the same protein have been identified for MAGEA2. MAGEA2 is a Protein Coding gene. Diseases associated with MAGEA2 include Melanoma and Dyskeratosis Congenita.